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A computerized analysis of the entire retinal ganglion cell population and its spatial distribution in adult rats.
| Tipo: | Artículo |
| Autores: | Salinas-Navarro M, Mayor-Torroglosa S, Jiménez-López M, Avilés-Trigueros M, Holmes TM, Lund RD, Villegas-Pérez MP, Vidal-Sanz M. |
| Títuto Revista: | Vision Research |
| Referencia: | |
| Centro: | 12 - EHU - GOBE |
A computerized analysis of the entire retinal ganglion cell population and its spatial distribution in adult rats.
Source
Laboratorio de Oftalmología Experimental, Facultad de Medicina, Universidad de Murcia, E-30100 Murcia, Spain.
Abstract
In adult albino (SD) and pigmented (PVG) rats the entire population of retinal ganglion cells (RGCs) was quantified and their spatial distribution analyzed using a computerized technique. RGCs were back-labelled from the optic nerves (ON) or the superior colliculi (SCi) with Fluorogold (FG). Numbers of RGCs labelled from the ON [SD: 82,818+/-3,949, n=27; PVG: 89,241+/-3,576, n=6) were comparable to those labelled from the SCi [SD: 81,486+/-4,340, n=37; PVG: 87,229+/-3,199; n=59]. Detailed methodology to provide cell density information at small scales demonstrated the presence of a horizontal region in the dorsal retina with highest densities, resembling a visual streak.
- PMID: 18952118 [PubMed - indexed for MEDLINE]
